The best Side of cees dekker
The best Side of cees dekker
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Working with solitary-molecule optical and AFM imaging and force-spectroscopy techniques, we seek to unravel the mechanistic components of the framework and dynamics of chromosomes. Our exploration passions consist of:
1996, initially mesoscopic charge density waves units; and initially electrical measurements on only one metallic nanocluster involving nanoelectrodes
‘It absolutely was simply just a make any difference of buying up a e-book on mobile biology and beginning to go through. I'd come from a entire world of extremely-significant vacuums, cryostats and quantum phenomena, and now I had been Performing at space temperature with molecular biology kits.
Deposition and atomic power microscopy of person phthalocyanine polymers involving nanofabricated electrodes
2010, formulated a new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by means of graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into sound-point out nanopores
Our analysis ranges from your biophysics of DNA to artificial cells and over and above. Make sure you take a look beneath with the spectrum of our existing assignments.
‘At first we looked at Organic units using a Bodily view and acted on the basis on the tools we understood. It took a several years right before we started out Performing extra on the big biological troubles. I then began to connect with it nanobiology, a term that did not exist at time.
Nanopores characterize a sublime and functional Software to evaluate single molecules. We study novel detection modes with solid-point out nanopores together with various ways to measure proteins with nanopores. Tasks encompass the subsequent:
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Pretty awesome, but that wasn’t genuinely where my curiosity lay. I planned to pioneer And that i had the feeling that was no more possible, because the most exciting essential insights had presently been uncovered. But my subject experienced developed several enjoyable new tools to measure personal molecules. I decided which i planned to apply this to biology, to look at it from a Bodily viewpoint.’
Testing pseudotopological and nontopological versions for SMC-pushed DNA loop extrusion against roadblock-traversal experiments
Nature Physics many thanks the anonymous reviewers for their contribution into the peer critique of this work.
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It had been an exceedingly fascinating time, through which I been given plenty of guidance from Delft College of Technologies, wherever I had been a professor at enough time, And that i began many collaborations with molecular biologists. That aided me master a great deal.’